Featured Publications

Disentangling speech and music in the auditory cortex

How does the developing brain process overlapping speech and music when they co-occur in naturalistic contexts?

Commentary in Brain

Converging and conflicting evidence for left temporal lobe in acoustic-phonetic perception

Brain responses during speaking and listening

New paper by Kurteff et al. in the Journal of Neuroscience shows how brain responses differ during speaking and listening in the auditory cortex and the insula

Speech and music in the brain

Brain stimulation can help us understand speech and music - read more in Frontiers for Young Minds!

All Publications

• Hamilton, L.S. (2025). Converging and conflicting evidence for left temporal lobe regions in acoustic-phonetic perception. Brain , 148 (4) , 1055--1057
• Kurteff, G.L., Field, A.M., Asghar, S., Tyler-Kabara, E.C., Clarke, D., Weiner, H.L., Anderson, A.E., Watrous, A.J., Buchanan, R.J., Modur, P.N., Hamilton, L.S. (2024). Spatiotemporal mapping of auditory onsets during speech production. Journal of Neuroscience , 44 (47) , , Web viewer
• Kurteff, G.L., Field, A.M., Asghar, S., Tyler-Kabara, E.C., Clarke, D., Weiner, H.L., Anderson, A.E., Watrous, A.J., Buchanan, R.J., Modur, P.N., Hamilton, L.S. (2024). Processing of auditory feedback in perisylvian and insular cortex. bioRxiv
• Hamilton, L.S. (2024). Neural Processing of Speech Using Intracranial Electroencephalography: Sound Representations in the Auditory Cortex. Oxford Research Encyclopedia of Neuroscience
• Desai, M., Field, A.M., Hamilton, L.S. (2024). A comparison of EEG encoding models using audiovisual stimuli and their unimodal counterparts. PLOS Computational Biology , 20 (9) , e1012433
• Hamilton, L., Asghar, S., Desai, M., Kurteff, G., Field, A., Nussbaum, N., Clarke, D., Tyler-Kabara, E., Anderson, A., Weiner, H. (2023). Utilizing Clinical Intracranial Epilepsy Monitoring Infrastructure for Basic Science Research of Speech and Language Development. ANNALS OF NEUROLOGY , 94 () , S66--S66
• Desai, M., Field, A.M., Hamilton, L.S. (2023). Dataset size considerations for robust acoustic and phonetic speech encoding models in EEG. Frontiers in Human Neuroscience , 16 , 1001171
• Kurteff, G.L., Lester-Smith, R.A., Martinez, A., Currens, N., Holder, J., Villarreal, C., Mercado, V.R., Truong, C., Huber, C., Pokharel, P., others (2023). Speaker-induced suppression in EEG during a naturalistic Reading and listening task. Journal of Cognitive Neuroscience , 35 (10) , 1538--1556
• Mercier, M.R., Dubarry, A., Tadel, F., Avanzini, P., Axmacher, N., Cellier, D., Del Vecchio, M., Hamilton, L.S., Hermes, D., Kahana, M.J., Knight, Robert,, Llorens, R,, Megevand, Pierre,, Melloni, Lucia,, Miller, Kai,, Piai, V,, Puce, Aina,, Ramsey, Nick,, Schwiedrzik, C,, Smith, S,, Stolk, A,, Swann, N,, Mariska, V,, Voytek, B,, Wang, L,, Lachaux, J-P,, Oostenveld, R. (2022). Advances in human intracranial electroencephalography research, guidelines and good practices. Neuroimage , 260 , 119438
• Hamilton, L.S. (2022). Human song: Separate neural pathways for melody and speech. Current Biology , 32 (7) , R311--R313
• Hamilton, L.S., Oganian, Y., Hall, J., Chang, E.F. (2021). Parallel and distributed encoding of speech across human auditory cortex. Cell , 184 (18) , 4626--4639 , Web viewer
• Ashmaig, O., Hamilton, L.S., Modur, P., Buchanan, R.J., Preston, A.R., Watrous, A.J. (2021). A platform for cognitive monitoring of neurosurgical patients during hospitalization. Frontiers in Human Neuroscience , 15 , 726998
• Sakthi, M., Desai, M., Hamilton, L., Tewfik, A. (2021). Keyword-spotting and speech onset detection in EEG-based Brain Computer Interfaces. 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER) , 519--522
• Kleen, J.K., Speidel, B.A., Baud, M.O., Rao, V.R., Ammanuel, S.G., Hamilton, L.S., Chang, E.F., Knowlton, R.C. (2021). Accuracy of omni-planar and surface casting of epileptiform activity for intracranial seizure localization. Epilepsia , 62 (4) , 947--959
• Desai, M., Holder, J., Villarreal, C., Clark, N., Hoang, B., Hamilton, L.S. (2021). Generalizable EEG encoding models with naturalistic audiovisual stimuli. Journal of Neuroscience , 41 (43) , 8946--8962
• Hamilton, L.S., Oganian, Y., Chang, E.F. (2020). Topography of speech-related acoustic and phonological feature encoding throughout the human core and parabelt auditory cortex. bioRxiv
• Desai, M., Sorrells, R., Leonard, M.K., Chang, E.F., Hamilton, L.S. (2020). Brain stimulation can help us understand music and language. Frontiers for Young Minds , 8 (16)
• Hamilton, L.S., Huth, A.G. (2020). The revolution will not be controlled: natural stimuli in speech neuroscience. Language, cognition and neuroscience , 35 (5) , 573--582
• Holdgraf, C., Appelhoff, S., Bickel, S., Bouchard, K., D’Ambrosio, S., David, O., Devinsky, O., Dichter, B., Flinker, A., Foster, B.L., others (2019). iEEG-BIDS, extending the Brain Imaging Data Structure specification to human intracranial electrophysiology. Scientific data , 6 (1) , 102
• Hamilton, L.S. (2019). The asymmetric auditory cortex. Nature Human Behaviour , 3 (4) , 327--328
• Holdgraf, C., Appelhoff, S., Bickel, S., Bouchard, K., D'Ambrosio, S., David, O., Devinsky, O., Dichter, B., Foster, B., Gorgolewski, C., others (2018). BIDS-iEEG: an extension to the brain imaging data structure (BIDS) specification for human intracranial electrophysiology.
• Breshears, J.D., Hamilton, L.S., Chang, E.F. (2018). Spontaneous neural activity in the superior temporal gyrus recapitulates tuning for speech features. Frontiers in Human Neuroscience , 12 , 360
• Hamilton, L.S., Edwards, E., Chang, E.F. (2018). A spatial map of onset and sustained responses to speech in the human superior temporal gyrus. Current Biology , 28 (12) , 1860--1871 , Video abstract
• Baud, M.O., Kleen, J.K., Anumanchipalli, G.K., Hamilton, L.S., Tan, Y., Knowlton, R., Chang, E.F. (2018). Unsupervised learning of spatiotemporal interictal discharges in focal epilepsy. Neurosurgery , 83 (4) , 683--691
• Hamilton, L.S., Chang, D.L., Lee, M.B., Chang, E.F. (2017). Semi-automated anatomical labeling and inter-subject warping of high-density intracranial recording electrodes in electrocorticography. Frontiers in neuroinformatics , 11 , 62
• Tang, C., Hamilton, L.S., Chang, E.F. (2017). Intonational speech prosody encoding in the human auditory cortex. Science , 357 (6353) , 797--801
• Hamilton, L.S., Edwards, E., Chang, E.F. (2016). Parallel streams define the temporal dynamics of speech processing across human auditory cortex. bioRxiv , 097485
• Muller, L., Hamilton, L.S., Edwards, E., Bouchard, K.E., Chang, E.F. (2016). Spatial resolution dependence on spectral frequency in human speech cortex electrocorticography. Journal of neural engineering , 13 (5) , 056013
• Cheung, C., Hamilton, L.S., Johnson, K., Chang, E.F. (2016). The auditory representation of speech sounds in human motor cortex. elife , 5 , e12577
• Hullett, P.W., Hamilton, L.S., Mesgarani, N., Schreiner, C.E., Chang, E.F. (2016). Human superior temporal gyrus organization of spectrotemporal modulation tuning derived from speech stimuli. Journal of Neuroscience , 36 (6) , 2014--2026
• Hamilton, L.S., Sohl-Dickstein, J., Huth, A.G., Carels, V.M., Deisseroth, K., Bao, S. (2013). Optogenetic activation of an inhibitory network enhances feedforward functional connectivity in auditory cortex. Neuron , 80 (4) , 1066--1076
• Elliott, T.M., Hamilton, L.S., Theunissen, F.E. (2013). Acoustic structure of the five perceptual dimensions of timbre in orchestral instrument tones. The Journal of the Acoustical Society of America , 133 (1) , 389--404
• Hamilton, L.S., Altshuler, L.L., Townsend, J., Bookheimer, S.Y., Phillips, O.R., Fischer, J., Woods, R.P., Mazziotta, J.C., Toga, A.W., Nuechterlein, K.H., Narr, K.L. (2009). Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task. Human brain mapping , 30 (12) , 3958--3969
• Hamilton, L.S., Levitt, J.G., O'Neill, J., Alger, J.R., Luders, E., Phillips, O.R., Caplan, R., Toga, A.W., McCracken, J., Narr, K.L. (2008). Reduced white matter integrity in attention-deficit hyperactivity disorder. Neuroreport , 19 (17) , 1705--1708
• Hamilton, L.S., Narr, K.L., Luders, E., Szeszko, P.R., Thompson, P.M., Bilder, R.M., Toga, A.W. (2007). Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia. Neuroreport , 18 (14) , 1427--1431